Abstract Facioscapulohumeral muscular dystrophy (FSHD) is caused by the epigenetic derepression of the 4q-linked D4Z4 macrosatellite repeat resulting in inappropriate expression of the D4Z4 repeat-encoded DUX4 gene in skeletal muscle.In 5% of FSHD ngetikin cases, D4Z4 chromatin relaxation is due to germline mutations in one of the chromatin modifie
Abstract Expanding applications in optical communications, computing, and sensing continue to drive the need for high-performance integrated photonic components.Designing these on-chip systems with arbitrary functionality requires beyond what is possible with physical intuition, for which machine learning-based methods have recently become popular.
Recently, the mobile wheeled inverted pendulum (MWIP) has gained an increasing ngetikin interest in the field of robotics due to traffic and environmental protection problems.However, the MWIP system is characterized by its nonlinearity, underactuation, time-varying parameters, and natural instability, which make its modeling and control challengin
Resumen: Este ensayo se basa en la ampliación y profundización de un escrito anterior titulado “Innovar para diversificar y favorecer el aprendizaje histórico mediante entornos virtuales”, que fue presentado en eventos académicos de la Universidad de Guadalajara y la Universidad Autónoma de Tamaulipas en México y en la Universidad de Extr
Abstract Impaired proteostasis is associated with normal aging and is accelerated in neurodegeneration.This impairment may lead to the accumulation of protein, which can be toxic to cells and tissue.In a subset of frontotemporal lobar degeneration with tau sukin body lotion woolworths pathology (FTLD-tau) cases, pathogenic mutations in the microtub